The symptoms of aging will disappear.. German scientists restore eighty-year-old cells back to the age of twenty

Symptoms of aging are gradual changes in the skin, bones, muscles, senses, and memory, and begin at the level of the body’s cells on the inside before appearing on the outside through the skin and general weakness that may affect a person.

Regarding this important stage of human life, German scientists recently announced that they had reset the blood cells of an eighty-year-old man so that these cells had a genetic age of 20 years! This will change the way we think about the symptoms of aging and its physical and psychological consequences, especially as the people of the world seek to achieve the third goal of the Sustainable Development Goals: good health and well-being.

of this You will find the starting point in the article The Earth Guards Foundation – The symptoms of aging will disappear.. German scientists restore eighty-year-old cells to twenty-year-olds – Details of the symptoms of aging that you should know, and details of the German scientific achievement that represents a sustainable step and a clear answer to the frequently asked question: Is aging Illness? So keep reading.

What is the concept of aging? What are its types?

Before we tell you the details of the new German scientific research, we briefly explain to you the concept of aging. It is a biological process in which the ability of cells and organs to regenerate and function efficiently declines over time. It should be noted here that aging is a natural process, but it increases the possibility of contracting several diseases, and these are diseases Aging that science is working to understand.

What are the symptoms of aging in adults?

It is also important to know that the symptoms of aging appear gradually in adults. That is, the symptoms do not appear all together or to the same extent in every person. Regardless of the degree to which the symptoms of aging appear from one person to another, there are common physical symptoms that everyone knows.

Among these symptoms we find that the skin loses its elasticity, wrinkles appear, muscle and bone mass weakens, vision and hearing decline, and cognitive symptoms begin slowly, and this is represented in serious diseases such as Alzheimer’s disease.

Symptoms of aging in women

Characterized by symptoms Aging in women with menopause, and the accompanying hormonal changes that may be reflected in bone density and skin. Therefore, bone health must be monitored periodically, especially after middle age.

Symptoms of aging in men

Men also usually notice a gradual decrease in muscle mass and their energy level, and this gradual change is in contrast to the sudden shift in women. It is a progression that makes the symptoms less noticeable at the beginning.

How do scientists measure biological age?

You may wonder: How do we know that a cell is younger? The answer can be found in epigenetic clocks, which are vital indicators that biologically estimate the age of cells. These clocks analyze the chemical modifications to the acid النووي (DNA)، وهي تعديلات تتراكم أو تتغير مع تقدم العمر.

خلايا في الثمانين تعود إلى العشرين

From this angle – the angle of aging symptoms and their biological and physical concept – researchers from Bonn University Hospital and the University of Bonn have succeeded in remarkably regenerating human cells in the laboratory. They reprogrammed primary red blood cells directly into stem cells from which neurons could be derived.

During this process, the molecular clocks that indicate the age of the cell were reset; Blood cells with a biological age of 80 years were transformed into stem cells with a molecular age of approximately 20 years; This is in the interest of efforts to achieve the sustainable development goals, especially the third goal: good health.

How was it possible to transform a blood cell into a nerve cell?

To understand this science, we must know that the human body contains hundreds of types of specialized cells, all of which originate from a single fertilized egg, and carry almost the same genetic instructions, except that they acquire specific roles during their development; Under normal conditions, a skin cell, for example, does not turn into a liver cell.

However, modern laboratory techniques have overcome these limitations, making it possible to reprogram mature cells to adopt different identities, such as transforming skin cells into cells capable of producing nervous tissue.

Role of transcription factors

This process depends on a group of proteins called transcription factor Transcription Factor, which regulates how genes are activated. By changing the genetic instructions that the cell follows, these proteins redirect its growth and give it a new identity.

Regarding this, Professor Oliver Brustel, Director of the Institute of Reconstructive Neurobiology at Bonn University Hospital, said: « This method made it possible to convert red blood cell precursors directly into neural stem cells. Previous experiments by the team have proven that the neurons generated in this way are able to successfully communicate with existing neurons after being transplanted into the brains of mice.

In the end, what Earth Defenders Foundation wants to say is that reprogramming human cells taken from an eighty-year-old human to a molecular state associated with a younger age opens the door to medicine. A new door to understanding aging, and puts scientific knowledge before a question that goes beyond prolonging life.

From the perspective of sustainable development, this research gains its importance from its connection to the third goal of the sustainable development goals, which is concerned with good health and well-being; Medical progress is linked to its ability to reduce suffering, reduce years of disability, enhance the independence of the elderly, and enable a healthier and more dignified life.